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Livres
Articles (318)
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NAD + Metabolism in Aging and Cancer

Demarest, Tyler G., Babbar, Mansi, Okur, Mustafa N., Dan, Xiuli, Croteau, Deborah L., Fakouri, Nima B., Mattson, Mark P., Bohr, Vilhelm A.

Journal:

Annual Review of Cancer Biology

Année:

2019

Langue:

english

Fichier:

PDF, 663 KB

english, 2019

Human RecQ Helicases in DNA Repair, Recombination, and Replication

Croteau, Deborah L., Popuri, Venkateswarlu, Opresko, Patricia L., Bohr, Vilhelm A.

Journal:

Annual Review of Biochemistry

Année:

2014

Langue:

english

Fichier:

PDF, 2.07 MB

english, 2014

Natural polyphenols as sirtuin 6 modulators

Rahnasto-Rilla, Minna, Tyni, Jonna, Huovinen, Marjo, Jarho, Elina, Kulikowicz, Tomasz, Ravichandran, Sarangan, A. Bohr, Vilhelm, Ferrucci, Luigi, Lahtela-Kakkonen, Maija, Moaddel, Ruin

Journal:

Scientific Reports

Année:

2018

Langue:

english

Fichier:

PDF, 2.12 MB

english, 2018

PHOTOTOXIC EFFECTS OF FOUR PSORALENS ON L1210 CELLS. THE CORRELATION WITH DNA INTERSTRAND CROSS-LINKING

Peter Eigil Nielsen, Vilhelm Bohr

Journal:

Photochemistry and Photobiology

Année:

1983

Langue:

english

Fichier:

PDF, 444 KB

english, 1983

Oxidative stress and mitochondrial DNA repair: implications for NRTIs induced DNA damage

Kazunari Hashiguchi, Vilhelm A. Bohr, Nadja C. de Souza-Pinto

Journal:

Mitochondrion

Année:

2004

Langue:

english

Fichier:

PDF, 166 KB

english, 2004

Sarcopenia, Aging and Prospective Interventional Strategies

Waltz, Tyler B., Fivenson, Elayne M., Morevati, Marya, Li, Chuanhao, Becker, Kevin G., Bohr, Vilhelm A., Fang, Evandro F.

Journal:

Current Medicinal Chemistry

Année:

2019

Fichier:

PDF, 689 KB

2019

Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer’s disease model

Zhang, Peisu, Kishimoto, Yuki, Grammatikakis, Ioannis, Gottimukkala, Kamalvishnu, Cutler, Roy G., Zhang, Shiliang, Abdelmohsen, Kotb, Bohr, Vilhelm A., Misra Sen, Jyoti, Gorospe, Myriam, Mattson, Mark

Journal:

Nature Neuroscience

Année:

2019

Langue:

english

Fichier:

PDF, 8.95 MB

english, 2019

Telomeric length in individuals and cell lines with altered p53 status

Patricia A. Kruk, Vilhelm A. Bohr

Journal:

Radiation Oncology Investigations

Année:

1999

Langue:

english

Fichier:

PDF, 525 KB

english, 1999

Roles of RECQ helicases in recombination based DNA repair, genomic stability and aging

Dharmendra Kumar Singh, Byungchan Ahn, Vilhelm A. Bohr

Journal:

Biogerontology

Année:

2009

Langue:

english

Fichier:

PDF, 455 KB

english, 2009

Eight hundred and seventy-five cases of bacterial meningitis Part I of a three-part series: Clinical data, prognosis, and the role of specialised hospital departments

Vilhelm Bohr, Bo Hansen, Ove Jessen, Niels Johnsen, Helge Kjersem, Henning S. Kristensen, Jørgen Nyboe, Niels Rasmussen

Journal:

Journal of Infection

Année:

1983

Langue:

english

Fichier:

PDF, 577 KB

english, 1983

The mechanics of base excision repair, and its relationship to aging and disease

David M. Wilson III, Vilhelm A. Bohr

Journal:

DNA Repair

Année:

2007

Langue:

english

Fichier:

PDF, 664 KB

english, 2007

Mitochondrial DNA repair and association with aging – An update

Ricardo Gredilla, Vilhelm A. Bohr, Tinna Stevnsner

Journal:

Experimental Gerontology

Année:

2010

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2010

The excitatory neurotransmitter glutamate stimulates DNA repair to increase neuronal resiliency

Jenq-Lin Yang, Peter Sykora, David M. Wilson III, Mark P. Mattson, Vilhelm A. Bohr

Journal:

Mechanisms of Ageing and Development

Année:

2011

Langue:

english

Fichier:

PDF, 894 KB

english, 2011

Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells

Vilhelm A Bohr

Journal:

Free Radical Biology and Medicine

Année:

2002

Langue:

english

Fichier:

PDF, 206 KB

english, 2002

Erling Christen Seeberg (1946–2004)

Errol C. Friedberg, Vilhelm A. Bohr, Robert P.P. Fuchs

Journal:

DNA Repair

Année:

2005

Langue:

english

Fichier:

PDF, 37 KB

english, 2005

107 Differential age-related changes in mitochondrial DNA repair activities in mouse brain regions

Ricardo Gredilla, Christian H. Garm, Rikke Holm, Lior Weissman, Vilhelm A. Bohr, Tinna Stevnsner

Journal:

Mitochondrion

Année:

2010

Langue:

english

Fichier:

PDF, 40 KB

english, 2010

142 Unraveling the potential role of human Suv3 in genome maintenance

Susanne T. Venoe, Cezar Pestana, Tomazs Kulikowicz, Tinna Stevnsner, Vilhelm A. Bohr

Journal:

Mitochondrion

Année:

2010

Langue:

english

Fichier:

PDF, 39 KB

english, 2010

141 Mitochondrial transcription factor a mitochondrial DNA repair

Deborah L. Croteau, Anne-Cécile V. Bayne, Chandrika Canugovi, Scott Maynard, Nadja de Souza-Pinto, Vilhelm A. Bohr

Journal:

Mitochondrion

Année:

2010

Langue:

english

Fichier:

PDF, 39 KB

english, 2010

RecQ helicases in DNA double strand break repair and telomere maintenance

Dharmendra Kumar Singh, Avik K. Ghosh, Deborah L. Croteau, Vilhelm A. Bohr

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

2012

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2012

Mitochondrial DNA repair of oxidative damage in mammalian cells

Vilhelm A. Bohr, Tinna Stevnsner, Nadja C. de Souza-Pinto

Journal:

Gene

Année:

2002

Langue:

english

Fichier:

PDF, 218 KB

english, 2002

An evolving bioinformatics tool reveals mitochondrial pathology in diseases and aging

Morten Scheibye-Knudsen, Karsten Scheibye-Alsing, Chandrika Canugovi, Deborah L. Croteau, Vilhelm A. Bohr

Journal:

Mitochondrion

Année:

2012

Langue:

english

Fichier:

PDF, 66 KB

english, 2012

BDNF and Exercise Enhance Neuronal DNA Repair by Stimulating CREB-Mediated Production of Apurinic/Apyrimidinic Endonuclease 1

Yang, Jenq-Lin, Lin, Yu-Ting, Chuang, Pei-Chin, Bohr, Vilhelm A., Mattson, Mark P.

Journal:

NeuroMolecular Medicine

Année:

2014

Langue:

english

Fichier:

PDF, 913 KB

english, 2014

Defective Mitophagy in XPA via PARP-1 Hyperactivation and NAD+/SIRT1 Reduction

Fang, Evandro Fei, Scheibye-Knudsen, Morten, Brace, Lear E., Kassahun, Henok, SenGupta, Tanima, Nilsen, Hilde, Mitchell, James R., Croteau, Deborah L., Bohr, Vilhelm A.

Journal:

Cell

Année:

2014

Langue:

english

Fichier:

PDF, 4.93 MB

english, 2014

Preferential DNA Repair of an Active Gene in Human Cells

Isabel Mellon, Vilhelm A. Bohr, Charles Allen Smith and Philip C. Hanawalt

Journal:

Proceedings of the National Academy of Sciences

Année:

1986

Langue:

english

Fichier:

PDF, 1.05 MB

english, 1986

Asbestos-Induced Pulmonary Fibrosis Is Augmented in 8-Oxoguanine DNA Glycosylase Knockout Mice

Cheresh, Paul, Morales-Nebreda, Luisa, Kim, Seok-Jo, Yeldandi, Anjana, Williams, David B., Cheng, Yuan, Mutlu, Gökhan M., Budinger, G. R. Scott, Ridge, Karen, Schumacker, Paul T., Bohr, Vilhelm A., Ka

Journal:

American Journal of Respiratory Cell and Molecular Biology

Année:

2015

Langue:

english

Fichier:

PDF, 1.96 MB

english, 2015

The role of DNA base excision repair in brain homeostasis and disease

Akbari, Mansour, Morevati, Marya, Croteau, Deborah, Bohr, Vilhelm A.

Journal:

DNA Repair

Année:

2015

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2015

DNA Damage, DNA Repair, Aging, and Neurodegeneration

Maynard, Scott, Fang, Evandro Fei, Scheibye-Knudsen, Morten, Croteau, Deborah L., Bohr, Vilhelm A.

Journal:

Cold Spring Harbor Perspectives in Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.00 MB

english, 2015

Increased deoxythymidine triphosphate levels is a feature of relative cognitive decline

Desler, Claus, Frederiksen, Jane H., Angleys, Maria, Maynard, Scott, Keijzers, Guido, Fagerlund, Birgitte, Mortensen, Erik Lykke, Osler, Merete, Lauritzen, Martin, Bohr, Vilhelm A., Rasmussen, Lene Ju

Journal:

Mitochondrion

Année:

2015

Langue:

english

Fichier:

PDF, 651 KB

english, 2015

NAD + in Aging: Molecular Mechanisms and Translational Implications

Fang, Evandro F., Lautrup, Sofie, Hou, Yujun, Demarest, Tyler G., Croteau, Deborah L., Mattson, Mark P., Bohr, Vilhelm A.

Journal:

Trends in Molecular Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 2.47 MB

english, 2017

Mitochondrial endogenous oxidative damage has been overestimated

ANSON, R. MICHAEL, HUDSON, EDGAR, BOHR, VILHELM A.

Journal:

The FASEB Journal

Année:

2000

Langue:

english

Fichier:

PDF, 321 KB

english, 2000

Toward understanding genomic instability, mitochondrial dysfunction and aging

Fakouri, Nima B., Hou, Yujun, Demarest, Tyler G., Christiansen, Louise S., Okur, Mustafa N., Mohanty, Joy G., Croteau, Deborah L., Bohr, Vilhelm A.

Journal:

FEBS Journal

Année:

2018

Langue:

english

Fichier:

PDF, 792 KB

english, 2018

Mitochondria in the signaling pathways that control longevity and health span

Akbari, Mansour, Kirkwood, Thomas B.L., Bohr, Vilhelm A.

Journal:

Ageing Research Reviews

Année:

2019

Fichier:

PDF, 4.12 MB

2019

Ageing as a risk factor for neurodegenerative disease

Hou, Yujun, Dan, Xiuli, Babbar, Mansi, Wei, Yong, Hasselbalch, Steen G., Croteau, Deborah L., Bohr, Vilhelm A.

Journal:

Nature Reviews Neurology (formerly Nature Clinical Practice Neurology)

Année:

2019

Langue:

english

Fichier:

PDF, 2.36 MB

english, 2019

The NAD+-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications

Aman, Yahyah, Frank, Johannes, Lautrup, Sofie Hindkjær, Matysek, Adrian, Niu, Zhangming, Yang, Guang, Shi, Liu, Bergersen, Linda H., Storm-Mathisen, Jon, Rasmussen, Lene J., Bohr, Vilhelm A., Nilsen,

Journal:

Mechanisms of Ageing and Development

Année:

2020

Fichier:

PDF, 2.02 MB

2020

Effect of aging on EGF-stimulated replication of specific genes in rat hepatocytes

Shoichi Kitano, Vilhelm A. Bohr, Tanya D. Reed, Cynthia M. Haggerty, Alfred May, George S. Roth

Journal:

Journal of Cellular Physiology

Année:

1998

Langue:

english

Fichier:

PDF, 269 KB

english, 1998

Pentoxifylline inhibits gene-specific repair of UV-induced DNA damage in hamster cells

Charles J. Link Jr., David Orren, Rebecca Muldoon, John A. Cook, Vilhelm A. Bohr

Journal:

Radiation Oncology Investigations

Année:

1996

Langue:

english

Fichier:

PDF, 613 KB

english, 1996

Identification of phage antibodies toward the Werner protein by selection on Western blots

Peter Ravn, Svend Kjær, Kristian Hobolt Jensen, Troels Wind, Kim Bak Jensen, Peter Kristensen, Robert M. Brosh, David K. Orren, Vilhelm A. Bohr, Brian F. C. Clark

Journal:

ELECTROPHORESIS

Année:

2000

Langue:

english

Fichier:

PDF, 336 KB

english, 2000

DNA repair and mutagenesis in Werner syndrome

Vilhelm A. Bohr, Nadja Souza Pinto, Simon G. Nyaga, Grigory Dianov, Kenneth Kraemer, Michael M. Seidman, Robert M. Brosh Jr.

Journal:

Environmental and Molecular Mutagenesis

Année:

2001

Langue:

english

Fichier:

PDF, 150 KB

english, 2001

Quantitation of 2-amino-3-methylimidazo[4,5-f]quinoline and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline DNA adducts in specific sequences using alkali or uvrABC excinuclease

Kazuhiro Nouso, Vilhelm A. Bohr, Herman A. J. Schut, Elizabeth G. Snyderwine

Journal:

Molecular Carcinogenesis

Année:

1993

Langue:

english

Fichier:

PDF, 909 KB

english, 1993

875 Cases of bacterial meningitis: Diagnostic procedures and the impact of preadmission antibiotic therapy Part III of a three-part series

Vilhelm Bohr, Niels Rasmussen, Bo Hansen, Helge Kjersem, Ove Jessen, Niels Johnsen, Henning S. Kristensen

Journal:

Journal of Infection

Année:

1983

Langue:

english

Fichier:

PDF, 525 KB

english, 1983

Pneumococcal meningitis: An evaluation of prognostic factors in 164 cases based on mortality and on a study of lasting sequelae

Vilhelm Bohr, Niels Rasmussen, Bo Hansen, Anders Gade, Helge Kjersem, Niels Johnsen, Olaf Paulson

Journal:

Journal of Infection

Année:

1985

Langue:

english

Fichier:

PDF, 909 KB

english, 1985

Third complementarity-determining region of mutated VH immunoglobulin genes contains shorter V, D, J, P, and N components than non-mutated genes

Karli Rosner, David B. Winter, Robert E. Tarone, Gunhild Lange Skovgaard, Vilhelm A. Bohr, Patricia J. Gearhart

Journal:

Immunology

Année:

2001

Langue:

english

Fichier:

PDF, 645 KB

english, 2001

The clinical characteristics of Werner syndrome: molecular and biochemical diagnosis

Meltem Muftuoglu, Junko Oshima, Cayetano von Kobbe, Wen-Hsing Cheng, Dru F. Leistritz, Vilhelm A. Bohr

Journal:

Human Genetics

Année:

2008

Langue:

english

Fichier:

PDF, 411 KB

english, 2008

Mitochondria, oxidative DNA damage, and aging

R. Michael Anson, Vilhelm A. Bohr

Journal:

AGE

Année:

2000

Langue:

english

Fichier:

PDF, 1.97 MB

english, 2000

Sequelae from bacterial meningitis and their relation to the clinical condition during acute illness, based on 667 questionnaire returns. Part II of a three part series

Vilhelm Bohr, Bo Hansen, Helge Kjersem, Niels Rasmussen, Niels Johnsen, Henning S. Kristensen, Ove Jessen

Journal:

Journal of Infection

Année:

1983

Langue:

english

Fichier:

PDF, 526 KB

english, 1983

TRF2 dysfunction elicits DNA damage responses associated with senescence in proliferating neural cells and differentiation of neurons

Peisu Zhang, Katsutoshi Furukawa, Patricia L. Opresko, Xiangru Xu, Vilhelm A. Bohr, Mark P. Mattson

Journal:

Journal of Neurochemistry

Année:

2006

Langue:

english

Fichier:

PDF, 1.66 MB

english, 2006

The involvement of human RECQL4 in DNA double-strand break repair

Dharmendra Kumar Singh, Parimal Karmakar, Maria Aamann, Shepherd H. Schurman, Alfred May, Deborah L. Croteau, Lynnette Burks, Sharon E. Plon, Vilhelm A. Bohr

Journal:

Aging Cell

Année:

2010

Langue:

english

Fichier:

PDF, 868 KB

english, 2010

Replication of an association of variation in the FOXO3A gene with human longevity using both case–control and longitudinal data

Mette Soerensen, Serena Dato, Kaare Christensen, Matt McGue, Tinna Stevnsner, Vilhelm A. Bohr, Lene Christiansen

Journal:

Aging Cell

Année:

2010

Langue:

english

Fichier:

PDF, 230 KB

english, 2010

The Cockayne syndrome group B protein is a functional dimer

Mette Christiansen, Tina Thorslund, Bjarne Jochimsen, Vilhelm A. Bohr, Tinna Stevnsner

Journal:

FEBS Journal

Année:

2005

Langue:

english

Fichier:

PDF, 216 KB

english, 2005

The Werner Syndrome: A Model for the Study of Human Aging

JAN O. NEHLIN, GUNHILD LANGE SKOVGAARD, VILHELM A. BOHR

Journal:

Annals of the New York Academy of Sciences

Année:

2000

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2000